The targetable nanoparticle BAF312@cRGD-CaP-NP represses tumor growth and angiogenesis by downregulating the S1PR1/P-STAT3/VEGFA axis in triple-negative breast cancer

BACKGROUND: Overexpressed vascular endothelial growth factor A (VEGFA) and phosphorylated signal transducer and activator of transcription 3 (P-STAT3) cause unrestricted tumor growth and angiogenesis of breast cancer (BRCA), especially triple-negative breast cancer (TNBC). Hence, novel treatment str...

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Detalles Bibliográficos
Autores principales: Gong, Ke, Jiao, Juyang, Xu, Chaoqun, Dong, Yang, Li, Dongxiao, He, Di, Zhao, De, Yu, Jian, Sun, Ying, Zhang, Wei, Bai, Min, Duan, Yourong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167992/
https://www.ncbi.nlm.nih.gov/pubmed/34059068
http://dx.doi.org/10.1186/s12951-021-00904-6

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