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Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients

BACKGROUND: Increased catabolism has recently been recognized as a clinical manifestation of amyotrophic lateral sclerosis (ALS). The hypothalamic systems have been shown to be involved in the metabolic dysfunction in ALS, but the exact extent of hypothalamic circuit alterations in ALS is yet to be...

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Detalles Bibliográficos
Autores principales:	Bayer, David, Antonucci, Stefano, Müller, Hans-Peter, Saad, Rami, Dupuis, Luc, Rasche, Volker, Böckers, Tobias M., Ludolph, Albert C., Kassubek, Jan, Roselli, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168014/ https://www.ncbi.nlm.nih.gov/pubmed/34059131 http://dx.doi.org/10.1186/s40035-021-00241-6

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