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Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 

BACKGROUND: Polyps of the uterine cervix are one of the most common benign hyperplastic lesions occurring in the female genital tract that usually arise from the endocervical canal and are believed to be the result of reactive changes due to long-standing chronic inflammation, multiparty, and foreig...

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Autores principales: Esmat, Esmatullah, Malakzai, Haider Ali, Haidari, Mujtaba, Haidary, Ahmed Maseh, Baha, Merwaise, Abdul-Ghafar, Jamshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168025/
https://www.ncbi.nlm.nih.gov/pubmed/34059119
http://dx.doi.org/10.1186/s13256-021-02878-3
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author Esmat, Esmatullah
Malakzai, Haider Ali
Haidari, Mujtaba
Haidary, Ahmed Maseh
Baha, Merwaise
Abdul-Ghafar, Jamshid
author_facet Esmat, Esmatullah
Malakzai, Haider Ali
Haidari, Mujtaba
Haidary, Ahmed Maseh
Baha, Merwaise
Abdul-Ghafar, Jamshid
author_sort Esmat, Esmatullah
collection PubMed
description BACKGROUND: Polyps of the uterine cervix are one of the most common benign hyperplastic lesions occurring in the female genital tract that usually arise from the endocervical canal and are believed to be the result of reactive changes due to long-standing chronic inflammation, multiparty, and foreign bodies. Cervical polyps are usually small in size (less than 4 cm) that are commonly found in adult women; however, a few cases of giant polyps and the rare occurrence of these lesions in children have also been reported. Heterotopias and malignant transformation in cervical polyps are considered to be very rare. CASE PRESENTATION: We present the case of a 10-year-old Afghan girl with a giant pedunculated mass protruding out of the uterine cervix that was accompanied by abdominal pain and mass sensation. The mass was completely excised by surgical intervention and the specimen was submitted for histopathological evaluation. Upon gross and microscopic examination, the characteristic findings of a hamartomatous polyp with heterologous mesenchymal tissue in the form of mature cartilage were seen. To the best of our knowledge, this is the first case of a giant (17.5 cm) hamartomatous polyp of the uterine cervix in this age group. CONCLUSION: Giant hamartomatous cervical polyps rarely occur in patients below 10 years of age. The majority of these lesions are benign; however, a few cases with malignant transformation are also reported, which demands elaborate investigations into the etiopathogenesis and nature of the lesions.
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spelling pubmed-81680252021-06-02 Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report  Esmat, Esmatullah Malakzai, Haider Ali Haidari, Mujtaba Haidary, Ahmed Maseh Baha, Merwaise Abdul-Ghafar, Jamshid J Med Case Rep Case Report BACKGROUND: Polyps of the uterine cervix are one of the most common benign hyperplastic lesions occurring in the female genital tract that usually arise from the endocervical canal and are believed to be the result of reactive changes due to long-standing chronic inflammation, multiparty, and foreign bodies. Cervical polyps are usually small in size (less than 4 cm) that are commonly found in adult women; however, a few cases of giant polyps and the rare occurrence of these lesions in children have also been reported. Heterotopias and malignant transformation in cervical polyps are considered to be very rare. CASE PRESENTATION: We present the case of a 10-year-old Afghan girl with a giant pedunculated mass protruding out of the uterine cervix that was accompanied by abdominal pain and mass sensation. The mass was completely excised by surgical intervention and the specimen was submitted for histopathological evaluation. Upon gross and microscopic examination, the characteristic findings of a hamartomatous polyp with heterologous mesenchymal tissue in the form of mature cartilage were seen. To the best of our knowledge, this is the first case of a giant (17.5 cm) hamartomatous polyp of the uterine cervix in this age group. CONCLUSION: Giant hamartomatous cervical polyps rarely occur in patients below 10 years of age. The majority of these lesions are benign; however, a few cases with malignant transformation are also reported, which demands elaborate investigations into the etiopathogenesis and nature of the lesions. BioMed Central 2021-06-01 /pmc/articles/PMC8168025/ /pubmed/34059119 http://dx.doi.org/10.1186/s13256-021-02878-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Esmat, Esmatullah
Malakzai, Haider Ali
Haidari, Mujtaba
Haidary, Ahmed Maseh
Baha, Merwaise
Abdul-Ghafar, Jamshid
Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
title Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
title_full Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
title_fullStr Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
title_full_unstemmed Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
title_short Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
title_sort giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report 
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168025/
https://www.ncbi.nlm.nih.gov/pubmed/34059119
http://dx.doi.org/10.1186/s13256-021-02878-3
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