EMBR-27. NEOPLASTIC AND IMMUNE SINGLE CELL TRANSCRIPTOMICS DEFINE SUBGROUP-SPECIFIC INTRA-TUMORAL HETEROGENEITY OF CHILDHOOD MEDULLOBLASTOMA

Medulloblastoma (MB) is a heterogeneous disease in which neoplastic cells and associated immune cells contribute to disease progression. To better understand cellular heterogeneity in MB we used single-cell RNA sequencing, immunohistochemistry and deconvolution of transcriptomic data to profile neop...

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Detalles Bibliográficos
Autores principales: Donson, Andrew, Riemondy, Kent, Venkataraman, Sujatha, Willard, Nicholas, Nellan, Anandani, Sanford, Bridget, Griesinger, Andrea, Amani, Vladimir, Mitra, Siddhartha, Hankinson, Todd, Handler, Michael, Sill, Martin, Ocasio, Jennifer, Weir, Seth, Malawsky, Daniel, Gershon, Timothy, Garancher, Alexandra, Wechsler-Reya, Robert, Hesselberg, Jay, Foreman, Nicholas, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Embryonal Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168088/
http://dx.doi.org/10.1093/neuonc/noab090.044

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