EMBR-22. RATIONAL DEVELOPMENT OF SYNERGISTIC THERAPIES ALONGSIDE BMI1 INHIBITION FOR GROUP 3 MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common pediatric brain tumor. Of its four distinct molecular subgroups, Group 3 MBs are associated with increased risk of recurrence, metastasis and overall poor patient outcome. In recent years, small molecule inhibitors targeting BMI1 have shown to be efficacious a...

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Detalles Bibliográficos
Autores principales: Bakhshinyan, David, Adile, Ashley A, Venugopal, Chitra, Brown, Kevin, Chan, Katherine, Qazi, Maleeha A, Chokshi, Chirayu, Gwynne, William D, Tieu, David, Moffat, Jason, Singh, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Embryonal Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168109/
http://dx.doi.org/10.1093/neuonc/noab090.040

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