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EPCT-22 SAFETY AND EFFICACY OF INTRAVENTRICULAR IMMUNOVIROTHERAPY WITH ONCOLYTIC HSV-1 G207 FOR TREATMENT OF LEPTOMENINGEAL DISEASE

Leptomeningeal metastatic disease (LMD) occurs in 30–50% of newly diagnosed and recurrent pediatric malignant cerebellar tumors and 20–45% of malignant supratentorial tumors. Radiation and chemotherapy often cause substantial long-term neurotoxicity and outcomes remain poor for patients with LMD. At...

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Detalles Bibliográficos
Autores principales:	Kang, Kyung-Don, Bernstock, Joshua, Mott, Bryan, Nan, Li, Li, Rong, Totsch, Stacie, Gary, Sam, Ghajar-Rahimi, Gelare, Etminan, Tina, Eisemann, Tanja, Wechsler-Reya, Robert, Beierle, Elizabeth, Gillespie, George, Markert, James, Friedman, Gregory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Translational/Early Phase Clinical Trials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168116/ http://dx.doi.org/10.1093/neuonc/noab090.208

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