TMOD-05. GENOME-WIDE DNA METHYLATION PROFILE: A POWERFUL STRATEGY TO RECAPITULATE HETEROGENEITY OF PEDIATRIC BRAIN TUMORS IN PRIMARY CELL LINES

BACKGROUND: Development of in vitro models of pediatric brain tumors (pBT) is instrumental for both understanding the contributing oncogenic molecular mechanisms and identifying and testing new therapeutic strategies. Primary cell lines should be established and managed to prevent epigenetic and gen...

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Detalles Bibliográficos
Autores principales: Pedace, Lucia, Pizzi, Simone, Vinci, Maria, Pericoli, Giulia, Catanzaro, Giuseppina, Abballe, Luana, Po, Agnese, Del Bufalo, Francesca, Rossi, Sabrina, Camassei, Francesca Diomedi, Giangaspero, Felice, Tiberi, Luca, Mastronuzzi, Angela, Ferretti, Elisabetta, Tartaglia, Marco, Locatelli, Franco, Ciolfi, Andrea, Miele, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Models
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168120/
http://dx.doi.org/10.1093/neuonc/noab090.146

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