LGG-08. TREATMENT OUTCOMES AND TOLERABILITY OF TRAMETINIB IN PROGRESSIVE CIRCUMSCRIBED LOW-GRADE GLIOMAS

Circumscribed low-grade gliomas comprise roughly one-third of pediatric CNS tumors. Most of these tumors are caused by activating mutations in the mitogen-activated protein kinase (MAPK) pathway. Drugs targeting the MAPK pathway are effective in other cancers and are being utilized in low-grade glio...

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Detalles Bibliográficos
Autores principales: Hanzlik, Emily, Archambault, Bridget, Dairi, Mays, Schroeder, Kristin, Patel, Mallika, Lipp, Eric S, Boucree, Song, Peters, Katherine, Ashley, David, Landi, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Low Grade Gliomas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168132/
http://dx.doi.org/10.1093/neuonc/noab090.132

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