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LGG-13. PILOCYTIC ASTROCYTOMAS WITH NOVEL BRAF FUSIONS DEMONSTRATE MAPK PATHWAY ACTIVATION

BACKGROUND: Pilocytic astrocytomas (PAs) are the most common pediatric low-grade glioma subtype. Oftentimes, PAs demonstrate somatic genetic alterations, the most common being the BRAF-KIAA1549 fusion, which results in constitutive activation of the MAPK pathway. Better understanding of the effects...

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Detalles Bibliográficos
Autores principales:	Chatwin, Hannah, Lind, Katherine, DeSisto, John, Sanford, Bridget, Gilani, Ahmed, Green, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Low Grade Gliomas
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168138/ http://dx.doi.org/10.1093/neuonc/noab090.137

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