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IMMU-16. TARGETING GLYPICAN 2 (GPC2) ON PEDIATRIC MALIGNANT BRAIN TUMORS WITH MRNA CAR T CELLS

Glypican 2 (GPC2) is a cell-surface oncoprotein initially identified in neuroblastoma, retinoblastoma, and medulloblastoma as an ideal target for immunotherapy (Cancer Cell, 2017). Here we evaluated GPC2 expression across the spectrum of pediatric brain tumors using RNA sequencing from specimens in...

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Detalles Bibliográficos
Autores principales:	Foster, Jessica, Griffin, Crystal, Stern, Allison, Brimley, Cameron, Buongervino, Samantha, Storm, Phillip, Barrett, David, Maris, John, Resnick, Adam, Bosse, Kristopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Immunology/Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168182/ http://dx.doi.org/10.1093/neuonc/noab090.123

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