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HGG-03. THE GLYCOSPHINGOLIPIDS METABOLISM IS A NOVEL TARGET IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMA
H3K27M-mutant diffuse midline glioma (H3K27M-mutant DMG) is a rare malignant brain tumour entity in children and adults with a median overall survival of around 12 months. Genomic and proteomic analysis may help to identify new target structures, however not all relevant targets are covered by these...
Autores principales: | Paret, Claudia, Sandhoff, Roger, El Malki, Khalifa, Frauenknecht, Katrin B M, Wingerter, Arthur, Lehmann, Nadine, Vewinger, Nadine, Faber, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168204/ http://dx.doi.org/10.1093/neuonc/noab090.069 |
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