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HGG-03. THE GLYCOSPHINGOLIPIDS METABOLISM IS A NOVEL TARGET IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMA

H3K27M-mutant diffuse midline glioma (H3K27M-mutant DMG) is a rare malignant brain tumour entity in children and adults with a median overall survival of around 12 months. Genomic and proteomic analysis may help to identify new target structures, however not all relevant targets are covered by these...

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Detalles Bibliográficos
Autores principales: Paret, Claudia, Sandhoff, Roger, El Malki, Khalifa, Frauenknecht, Katrin B M, Wingerter, Arthur, Lehmann, Nadine, Vewinger, Nadine, Faber, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168204/
http://dx.doi.org/10.1093/neuonc/noab090.069

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