HGG-15. THE IMIPRIDONE ONC201 IN COMBINATION WITH THE ONCOLYTIC ADENOVIRUS DELTA-24-RGD HAS A SYNERGISTIC EFFECT IN PRECLINICAL MODELS OF PHGGS AND DMGS

Pediatric High Grade Gliomas (pHGGs), including Diffuse Midline Gliomas (DMGs), are aggressive pediatric tumors with a poor overall survival. In the last years, ONC201 has emerged as a promising agent in the field of pediatric brain tumors. Another interesting approach is virotherapy; Delta-24-RGD,...

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Detalles Bibliográficos
Autores principales: de la Nava, Daniel, Ausejo-Mauleon, Iker, Laspidea, Virginia, Marrodán, Lucía, Zalacain, Marta, Herrador-Cañete, Guillermo, Nazarian, Javad, Mueller, Sabine, Allen, Joshua E, Fueyo, Juan, Gomez-Manzano, Candelaria, Gupta, Sumit, Patiño, Ana, Alonso, Marta M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
High Grade Gliomas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168206/
http://dx.doi.org/10.1093/neuonc/noab090.081

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