EMBR-25. GENOME-WIDE GENETIC AND EPIGENETIC ASSESSMENT OF GROUP 4 MEDULLOBLASTOMA FOR IMPROVED, BIOMARKER DRIVEN, PROGNOSTICATION AND RISK-STRATIFICATION

INTRODUCTION: Medulloblastoma (MB) is the most common malignant brain tumour in children. The most frequent molecular subgroup, Group 4 (MB(Grp4)) accounts for ~35/40% of cases, however it has the least understood underlying biology. Clinical outcomes are heterogeneous in MB(Grp4) and are not accoun...

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Detalles Bibliográficos
Autores principales: Goddard, Jack, Castle, Jemma, Southworth, Emily, Crosier, Stephen, Martin-Guerrero, Idoia, Garcia-Ariza, Miguel, Navajas, Aurora, Bourdeaut, Franck, Dufour, Christelle, Goschzik, Tobias, Pietsch, Torsten, Williamson, Dan, Bailey, Simon, Schwalbe, Ed, Clifford, Steven, Hicks, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Embryonal Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168208/
http://dx.doi.org/10.1093/neuonc/noab090.043

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