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LGG-09. SENOLYTIC AGENT NAVITOCLAX TARGETS VINBLASTINE- AND MAPK INHIBITORS-INDUCED SENESCENT TUMOUR CELLS IN PAEDIATRIC LOW GRADE GLIOMAS

Pilocytic astrocytoma (PA, WHO grade I), the most common paediatric brain tumour, is characterized by constitutive activation of the MAPK pathway. PA tumours show a slow growth, without tendency to progress to high-grade malignancies. However, a significant group of patients for whom a total resecti...

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Detalles Bibliográficos
Autores principales:	Guiho, Romain, Selt, Florian, Stone, Thomas, Jacques, Thomas, Hargrave, Darren, Gil, Jesús, Witt, Olaf, Milde, Till, Barbera, Juan Pedro Martinez
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Low Grade Gliomas
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168216/ http://dx.doi.org/10.1093/neuonc/noab090.133

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