OMIC-11. SINGLE CELL RNA SEQUENCING FROM THE CSF OF SUBJECTS WITH H3K27M+ DIPG/DMG TREATED WITH GD2 CAR T-CELLULAR THERAPY

INTRODUCTION: We are conducting a Phase I clinical trial utilizing chimeric antigen receptor (CAR) T-cells targeting GD2 (NCT04196413) for H3K27M-mutant diffuse intrinsic pontine glioma (DIPG) and spinal cord diffuse midline glioma (DMG). Cerebrospinal fluid (CSF) is collected for correlative studie...

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Detalles Bibliográficos
Autores principales: Mochizuki, Aaron, Ramakrishna, Sneha, Good, Zina, Patel, Shabnum, Chinnasamy, Harshini, Yeom, Kristen, Schultz, Liora, Richards, Rebecca, Campen, Cynthia, Reschke, Agnes, Mahdi, Jasia, Toland, Angus, Baggot, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Landrum, Kayla, Erickson, Courtney, Rasmussen, Lindsey, Barsan, Valentin, Tamaresis, John, Marcy, Anne, Kunicki, Michael, Celones, Michelle, Ehlinger, Zach, Kurra, Sreevidya, Cornell, Timothy, Partap, Sonia, Fisher, Paul, Grant, Gerald, Vogel, Hannes, Davis, Kara, Feldman, Steven, Sahaf, Bita, Majzner, Robbie, Mackall, Crystal, Monje, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Omics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168255/
http://dx.doi.org/10.1093/neuonc/noab090.158

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