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EMBR-10. INOSITOL TREATMENT INHIBITS MEDULLOBLASTOMA THROUGH SUPPRESSION OF EPIGENETIC-DRIVEN METABOLIC ADAPTATION

Medulloblastoma (MB) is the most common paediatric malignant brain tumour and is classified into four distinct molecular subgroups (WNT, SHH, G3 and G4), each of them further subdivided into subtypes with different prognosis and responses to therapy. Deregulation of chromatin modifier genes plays an...

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Detalles Bibliográficos
Autores principales: Badodi, Sara, Pomella, Nicola, Zhang, Xinyu, Morrison, Gillian, Pollard, Steve M, Bennett, Christopher D, Clifford, Steven C, Peet, Andrew, Marino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168266/
http://dx.doi.org/10.1093/neuonc/noab090.028

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