Virology features of a family cluster of SARS-CoV-2 infections in Shanghai, China

The global spread of SARS-CoV-2 is currently continuing, and the World Health Organization has announced the risk assessment of the viruses as high. In this study, we analyzed virology features of SARS-CoV-2 causing a family cluster outbreak. Among the six family members, five have been laboratory-c...

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Detalles Bibliográficos
Autores principales: Zhou, Yanqiu, Teng, Zheng, Chen, Hongyou, Cui, Xiaoxian, Fang, Fanghao, Mou, Jiabin, Jiang, Hui, Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association Publishing House. Published by Elsevier BV. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168300/
https://www.ncbi.nlm.nih.gov/pubmed/34095806
http://dx.doi.org/10.1016/j.bsheal.2021.05.003
Descripción
Sumario:The global spread of SARS-CoV-2 is currently continuing, and the World Health Organization has announced the risk assessment of the viruses as high. In this study, we analyzed virology features of SARS-CoV-2 causing a family cluster outbreak. Among the six family members, five have been laboratory-confirmed infection of SARS-CoV-2 viruses. A total of five SARS-CoV-2 viruses have been isolated from the nasopharyngeal swabs. The complete genome of the viruses exhibited 100% nucleotide identity with each other. Only two nucleotide differences have been observed between genomes of the isolated viruses and the HCoV/Wuhan/ IVDC-HB-01/2019 strain. Therefore, SARS-CoV-2 has been confirmed as the causation of the family cluster infections.

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