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Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain
Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays key roles in the replication cycle and is a critical serological marker. Here, we characterize essential biochemical properties of N and describe the utility of these insights in serological studies. We de...
Autores principales: | Wu, Chao, Qavi, Abraham J., Hachim, Asmaa, Kavian, Niloufar, Cole, Aidan R., Moyle, Austin B., Wagner, Nicole D., Sweeney-Gibbons, Joyce, Rohrs, Henry W., Gross, Michael L., Peiris, J. S. Malik, Basler, Christopher F., Farnsworth, Christopher W., Valkenburg, Sophie A., Amarasinghe, Gaya K., Leung, Daisy W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168301/ https://www.ncbi.nlm.nih.gov/pubmed/34095780 http://dx.doi.org/10.1016/j.isci.2021.102681 |
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