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DHA intake relates to better cerebrovascular and neurodegeneration neuroimaging phenotypes in middle-aged adults at increased genetic risk of Alzheimer disease
BACKGROUND: The number of APOE-ε4 alleles is a major nonmodifiable risk factor for sporadic Alzheimer disease (AD). There is increasing evidence on the benefits of dietary DHA (22:6n–3) before the onset of AD symptoms, particularly in APOE-ε4 carriers. Brain alterations in the preclinical stage can...
Autores principales: | Sala-Vila, Aleix, Arenaza-Urquijo, Eider M, Sánchez-Benavides, Gonzalo, Suárez-Calvet, Marc, Milà-Alomà, Marta, Grau-Rivera, Oriol, González-de-Echávarri, José M, Crous-Bou, Marta, Minguillón, Carolina, Fauria, Karine, Operto, Grégory, Falcón, Carles, Salvadó, Gemma, Cacciaglia, Raffaele, Ingala, Silvia, Barkhof, Frederik, Schröder, Helmut, Scarmeas, Nikolaos, Gispert, Juan-Domingo, Molinuevo, José L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168359/ https://www.ncbi.nlm.nih.gov/pubmed/33733657 http://dx.doi.org/10.1093/ajcn/nqab016 |
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