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Fc-engineered antibody therapeutics with improved efficacy against COVID-19
Monoclonal antibodies (mAbs) with neutralizing activity against SARS-CoV-2 have demonstrated clinical benefit in cases of mild to moderate SARS-CoV-2 infection, substantially reducing the risk for hospitalization and severe disease(1–4). Treatment generally requires the administration of high doses...
Autores principales: | Yamin, Rachel, Jones, Andrew T, Hoffmann, Hans-Heinrich, Kao, Kevin S, Francis, Rebecca L, Sheahan, Timothy P, Baric, Ralph S, Rice, Charles M, Ravetch, Jeffrey V, Bournazos, Stylianos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168397/ https://www.ncbi.nlm.nih.gov/pubmed/34075373 http://dx.doi.org/10.21203/rs.3.rs-555612/v1 |
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