DNA–polymer conjugates via the graft-through polymerisation of native DNA in water

The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protecti...

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Detalles Bibliográficos
Autores principales: Arkinstall, Lucy A., Husband, Jonathan T., Wilks, Thomas R., Foster, Jeffrey C., O'Reilly, Rachel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168459/
https://www.ncbi.nlm.nih.gov/pubmed/33954310
http://dx.doi.org/10.1039/d0cc08008j
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author Arkinstall, Lucy A.
Husband, Jonathan T.
Wilks, Thomas R.
Foster, Jeffrey C.
O'Reilly, Rachel K.
author_facet Arkinstall, Lucy A.
Husband, Jonathan T.
Wilks, Thomas R.
Foster, Jeffrey C.
O'Reilly, Rachel K.
author_sort Arkinstall, Lucy A.
collection PubMed
description The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protection of the DNA bases.
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spelling pubmed-81684592021-06-11 DNA–polymer conjugates via the graft-through polymerisation of native DNA in water Arkinstall, Lucy A. Husband, Jonathan T. Wilks, Thomas R. Foster, Jeffrey C. O'Reilly, Rachel K. Chem Commun (Camb) Chemistry The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protection of the DNA bases. The Royal Society of Chemistry 2021-04-24 /pmc/articles/PMC8168459/ /pubmed/33954310 http://dx.doi.org/10.1039/d0cc08008j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Arkinstall, Lucy A.
Husband, Jonathan T.
Wilks, Thomas R.
Foster, Jeffrey C.
O'Reilly, Rachel K.
DNA–polymer conjugates via the graft-through polymerisation of native DNA in water
title DNA–polymer conjugates via the graft-through polymerisation of native DNA in water
title_full DNA–polymer conjugates via the graft-through polymerisation of native DNA in water
title_fullStr DNA–polymer conjugates via the graft-through polymerisation of native DNA in water
title_full_unstemmed DNA–polymer conjugates via the graft-through polymerisation of native DNA in water
title_short DNA–polymer conjugates via the graft-through polymerisation of native DNA in water
title_sort dna–polymer conjugates via the graft-through polymerisation of native dna in water
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168459/
https://www.ncbi.nlm.nih.gov/pubmed/33954310
http://dx.doi.org/10.1039/d0cc08008j
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