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Challenges Posed by Immune Responses to AAV Vectors: Addressing Root Causes
Host immune responses that limit durable therapeutic gene expression and cause clinically significant inflammation remain a major barrier to broadly successful development of adeno-associated virus (AAV)-based human gene therapies. In this article, mechanisms of humoral and cellular immune responses...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168460/ https://www.ncbi.nlm.nih.gov/pubmed/34084173 http://dx.doi.org/10.3389/fimmu.2021.675897 |