Mobilization efficiency is critically regulated by fat via marrow PPARδ

The efficiency of mobilization of hematopoietic stem/progenitor cells from bone marrow into the circulation by granulocyte colony-stimulating factor (G-CSF) is extremely varied in humans and mice and a mechanistic explanation for poor mobilizers is lacking. A mechanism of regulating mobilization eff...

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Detalles Bibliográficos
Autores principales: Suzuki, Tomohide, Ishii, Shinichi, Shinohara, Masakazu, Kawano, Yuko, Wakahashi, Kanako, Kawano, Hiroki, Sada, Akiko, Minagawa, Kentaro, Hamada, Michito, Takahashi, Satoru, Furuyashiki, Tomoyuki, Tan, Nguan Soon, Matsui, Toshimitsu, Katayama, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168511/
https://www.ncbi.nlm.nih.gov/pubmed/33538151
http://dx.doi.org/10.3324/haematol.2020.265751

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