Cargando…

The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution

OBJECTIVE: Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and various immune cells are involved in the initiation, progression, and regulation of SLE. Our goal was to reveal the chromatin accessibility landscape of peripheral blood mononuclear cells (PBMCs) in SLE patients at si...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Haiyan, Hong, Xiaoping, Wu, Hongwei, Zheng, Fengping, Zeng, Zhipeng, Dai, Weier, Yin, Lianghong, Liu, Dongzhou, Tang, Donge, Dai, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168536/ https://www.ncbi.nlm.nih.gov/pubmed/34084162 http://dx.doi.org/10.3389/fimmu.2021.641886

Ejemplares similares

Integrated analysis of competing endogenous RNA networks in peripheral blood mononuclear cells of systemic lupus erythematosus
por: Song, Wencong, et al.
Publicado: (2021)

Gene-regulatory network analysis of ankylosing spondylitis with a single-cell chromatin accessible assay
por: Yu, Haiyan, et al.
Publicado: (2020)

Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus
por: He, Jingquan, et al.
Publicado: (2022)

The identification of circular RNAs from peripheral blood mononuclear cells in systemic lupus erythematosus
por: Zheng, Fengping, et al.
Publicado: (2021)

Microbiome and Metabolome Analyses Reveal the Disruption of Lipid Metabolism in Systemic Lupus Erythematosus
por: He, Jingquan, et al.
Publicado: (2020)

Immune cell and TCR/BCR repertoire profiling in systemic lupus erythematosus patients by single-cell sequencing
por: Zheng, Fengping, et al.
Publicado: (2021)

Integrated proteome and phosphoproteome analyses of peripheral blood mononuclear cells in primary Sjögren syndrome patients
por: Huang, Shaoying, et al.
Publicado: (2020)

Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus erythematosus
por: Li, Yixi, et al.
Publicado: (2022)

Single-cell chromatin accessibility landscape of human umbilical cord blood in trisomy 18 syndrome
por: Qiu, Xiaofen, et al.
Publicado: (2021)

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Peripheral Mononuclear Cells in Patients With Ankylosing Spondylitis
por: Xu, Huixuan, et al.
Publicado: (2021)

Global Phosphoproteomics Unveils Kinase-Regulated Networks in Systemic Lupus Erythematosus
por: Meng, Shuhui, et al.
Publicado: (2022)

Screening Biomarkers for Systemic Lupus Erythematosus Based on Machine Learning and Exploring Their Expression Correlations With the Ratios of Various Immune Cells
por: Zhong, Yafang, et al.
Publicado: (2022)

Proteomics analysis of lysine crotonylation and 2-hydroxyisobutyrylation reveals significant features of systemic lupus erythematosus
por: Xie, Ting, et al.
Publicado: (2022)

Single-Cell RNA and ATAC Sequencing Reveal Hemodialysis-Related Immune Dysregulation of Circulating Immune Cell Subpopulations
por: Wu, Hongwei, et al.
Publicado: (2022)

Integrated single-cell analyses decode the developmental landscape of the human fetal spine
por: Yu, Haiyan, et al.
Publicado: (2022)

Analysis of gut microbiota and metabolites in patients with rheumatoid arthritis and identification of potential biomarkers
por: Chen, Yumei, et al.
Publicado: (2021)

Spatial proteomics landscape and immune signature analysis of renal sample of lupus nephritis based on laser-captured microsection
por: Zheng, Fengping, et al.
Publicado: (2023)

Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4(+) T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome
por: Hong, Xiaoping, et al.
Publicado: (2021)

Transcriptional Landscape of Enhancer RNAs in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus
por: Guo, Gangqiang, et al.
Publicado: (2022)

Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells
por: Li, Chunhong, et al.
Publicado: (2021)

Global Proteomic Analyses Reveals Abnormal Immune Regulation in Patients With New Onset Ankylosing Spondylitis
por: Yu, Zongchao, et al.
Publicado: (2022)

Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney
por: Wu, Hongwei, et al.
Publicado: (2022)

Correction to: Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney
por: Wu, Hongwei, et al.
Publicado: (2022)

Qualitative Proteome-wide Lysine Crotonylation Profiling Reveals Protein Modification Alteration in the Leukocyte Extravasation Pathway in Systemic Lupus Erythematosus
por: Zeng, Huiyi, et al.
Publicado: (2023)

Identification of a novel interplay between intestinal bacteria and metabolites in Chinese patients with IgA nephropathy via integrated microbiome and metabolome approaches
por: Wu, Hongwei, et al.
Publicado: (2021)

The accessible chromatin landscape of the murine hippocampus at single-cell resolution
por: Sinnamon, John R., et al.
Publicado: (2019)

Dysbiosis in Peripheral Blood Mononuclear Cell Virome Associated With Systemic Lupus Erythematosus
por: Guo, Gangqiang, et al.
Publicado: (2020)

Multiple Functions of B Cells in the Pathogenesis of Systemic Lupus Erythematosus
por: Ma, Kongyang, et al.
Publicado: (2019)

The Genetic Landscape of Cutaneous Lupus Erythematosus
por: Chen, Henry W., et al.
Publicado: (2022)

Screening biomarkers for Sjogren’s Syndrome by computer analysis and evaluating the expression correlations with the levels of immune cells
por: Zhong, Yafang, et al.
Publicado: (2023)

Multi-omics analyses of human colorectal cancer revealed three mitochondrial genes potentially associated with poor outcomes of patients
por: Zhang, Wei, et al.
Publicado: (2021)

Microbiome and metabolome analysis to clarify the interaction between the urine microbiota and serum metabolites in Chinese patients with immunoglobulin A nephropathy
por: Li, Shishi, et al.
Publicado: (2022)

Urinary microbiota and serum metabolite analysis in patients with diabetic kidney disease
por: Yang, Yan, et al.
Publicado: (2023)

Increased interleukin-23 receptor(+ )T cells in peripheral blood mononuclear cells of patients with systemic lupus erythematosus
por: Puwipirom, Hathaipat, et al.
Publicado: (2010)

Integrated analysis of mRNA, microRNA and protein in systemic lupus erythematosus-specific induced pluripotent stem cells from urine
por: Tang, Donge, et al.
Publicado: (2016)

Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus
por: Su, Yu-Jih, et al.
Publicado: (2014)

RNA-seq analysis of molecular heterogeneity peripheral blood mononuclear cells in systemic lupus erythematosus
por: Xue, Ke, et al.
Publicado: (2019)

Chromatin landscapes and genetic risk in systemic lupus
por: Hui-Yuen, Joyce S., et al.
Publicado: (2016)

Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer
por: Dai, Weier, et al.
Publicado: (2019)

Belimumab Decreases Autophagy and Citrullination in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus
por: Colasanti, Tania, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6b3b6onfa51cd70cicrd1glluu