A myocardin-adjacent lncRNA balances SRF-dependent gene transcription in the heart

Myocardin, a potent coactivator of serum response factor (SRF), competes with ternary complex factor (TCF) proteins for SRF binding to balance opposing mitogenic and myogenic gene programs in cardiac and smooth muscle. Here we identify a cardiac lncRNA transcribed adjacent to myocardin, named CARDIN...

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Detalles Bibliográficos
Autores principales: Anderson, Douglas M., Anderson, Kelly M., Nelson, Benjamin R., McAnally, John R., Bezprozvannaya, Svetlana, Shelton, John M., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168554/
https://www.ncbi.nlm.nih.gov/pubmed/33985971
http://dx.doi.org/10.1101/gad.348304.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168554/
https://www.ncbi.nlm.nih.gov/pubmed/33985971
http://dx.doi.org/10.1101/gad.348304.121

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