Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

Steps of mRNA maturation are important gene regulatory events that occur in distinct cellular locations. However, transcriptomic analyses often lose information on the subcellular distribution of processed and unprocessed transcripts. We generated extensive RNA-seq data sets to track mRNA maturation...

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Detalles Bibliográficos
Autores principales: Yeom, Kyu-Hyeon, Pan, Zhicheng, Lin, Chia-Ho, Lim, Han Young, Xiao, Wen, Xing, Yi, Black, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168582/
https://www.ncbi.nlm.nih.gov/pubmed/33832989
http://dx.doi.org/10.1101/gr.273904.120

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