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Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome

Programmed ribosomal frameshifting is a key event during translation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA genome that allows synthesis of the viral RNA-dependent RNA polymerase and downstream proteins. Here, we present the cryo–electron microscopy structure of a tr...

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Detalles Bibliográficos
Autores principales: Bhatt, Pramod R., Scaiola, Alain, Loughran, Gary, Leibundgut, Marc, Kratzel, Annika, Meurs, Romane, Dreos, René, O’Connor, Kate M., McMillan, Angus, Bode, Jeffrey W., Thiel, Volker, Gatfield, David, Atkins, John F., Ban, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168617/
https://www.ncbi.nlm.nih.gov/pubmed/34029205
http://dx.doi.org/10.1126/science.abf3546