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Programmed cell death 1 ligand (PD-L1) on T cells generates Treg suppression from memory

A recent study shows that programmed cell death 1 ligand (PD-L1) on activated T cells promotes their conversion to suppressive inducible regulatory T cells (iTregs), preferentially from among memory T cells. This new mechanism may normally protect against autoimmunity but is dysregulated in rheumato...

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Detalles Bibliográficos
Autores principales:	Kazanova, Alexandra, Rudd, Christopher E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Primer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168839/ https://www.ncbi.nlm.nih.gov/pubmed/34010274 http://dx.doi.org/10.1371/journal.pbio.3001272

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