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Division of labor of Y-family polymerases in translesion-DNA synthesis for distinct types of DNA damage
Living organisms are continuously under threat from a vast array of DNA-damaging agents, which impact genome DNA. DNA replication machinery stalls at damaged template DNA. The stalled replication fork is restarted via bypass replication by translesion DNA-synthesis polymerases, including the Y-famil...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168857/ https://www.ncbi.nlm.nih.gov/pubmed/34061890 http://dx.doi.org/10.1371/journal.pone.0252587 |