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Division of labor of Y-family polymerases in translesion-DNA synthesis for distinct types of DNA damage

Living organisms are continuously under threat from a vast array of DNA-damaging agents, which impact genome DNA. DNA replication machinery stalls at damaged template DNA. The stalled replication fork is restarted via bypass replication by translesion DNA-synthesis polymerases, including the Y-famil...

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Detalles Bibliográficos
Autores principales: Inomata, Yuriko, Abe, Takuya, Tsuda, Masataka, Takeda, Shunichi, Hirota, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168857/
https://www.ncbi.nlm.nih.gov/pubmed/34061890
http://dx.doi.org/10.1371/journal.pone.0252587