Cargando…

Clinical Efficacy of Polymyxin B in Patients Infected with Carbapenem-Resistant Organisms

PURPOSE: Carbapenem-resistant organisms (CROs) pose great challenges for clinical treatment. Polymyxin B (PMB) is one of the “last resort” choices of CRO infections. We explored the possible factors affecting PMB efficacy. PATIENTS AND METHODS: This retrospective study involved CRO-infected patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Qiong, Li, Guo-Hua, Qu, Qiang, Zhu, Hai-Hong, Luo, Yue, Yan, Han, Yuan, Hai-Yan, Qu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168961/ https://www.ncbi.nlm.nih.gov/pubmed/34093026 http://dx.doi.org/10.2147/IDR.S312708

Ejemplares similares

A Comparative Study of the Microbiological Efficacy of Polymyxin B on Different Carbapenem-Resistant Gram-Negative Bacteria Infections
por: Lu, Qiong, et al.
Publicado: (2021)

Polymyxin B-Based Regimens for Patients Infected with Carbapenem-Resistant Gram-Negative Bacteria: Clinical and Microbiological Efficacy, Mortality, and Safety
por: Qu, Jian, et al.
Publicado: (2022)

Nephrotoxicity and Efficacy Assessment of Polymyxin B Use in Renal Transplant Patients
por: Wen, Yu-Xin, et al.
Publicado: (2022)

Efficacy and safety of polymyxin B in carbapenem-resistant gram-negative organisms infections
por: Xia, G. L., et al.
Publicado: (2021)

Polymyxin B-Associated Nephrotoxicity and Its Predictors: A Retrospective Study in Carbapenem-Resistant Gram-Negative Bacterial Infections
por: Wu, Xiao-Li, et al.
Publicado: (2022)

Efficacy and safety of polymyxin E sulfate in the treatment of critically ill patients with carbapenem-resistant organism infections
por: Lu, Xin, et al.
Publicado: (2022)

Polymyxin B Etest Fails to Distinguish Carbapenem-resistant Enterobacteriaceae with Elevated Polymyxin B MICs
por: Kulengowski, Brandon, et al.
Publicado: (2017)

Efficacy and nephrotoxicity of polymyxin B in elderly patients with carbapenem resistant bacterial infection
por: Xia, G. L., et al.
Publicado: (2023)

Polymyxin B/Tigecycline Combination vs. Polymyxin B or Tigecycline Alone for the Treatment of Hospital-Acquired Pneumonia Caused by Carbapenem-Resistant Enterobacteriaceae or Carbapenem-Resistant Acinetobacter baumannii
por: Chang, Kang, et al.
Publicado: (2022)

Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin
por: Jin, Xi, et al.
Publicado: (2021)

Combined effect of Polymyxin B and Tigecycline to overcome Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae
por: Tian, Yuan, et al.
Publicado: (2021)

The Efficacy and Influencing Factors of Polymyxin B in High-Level Carbapenem-Resistant Klebsiella pneumoniae Infections
por: Jia, Xuedong, et al.
Publicado: (2023)

Polymyxin B Resistance in Carbapenem-Resistant Klebsiella pneumoniae, São Paulo, Brazil
por: Bartolleti, Flávia, et al.
Publicado: (2016)

Use of polymyxins for carbapenem-resistant infections in children and adolescents
por: Barco-Cabrera, Carolina, et al.
Publicado: (2022)

Pharmacokinetics/pharmacodynamics of polymyxin B in patients with bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniae
por: Yu, Zhenwei, et al.
Publicado: (2022)

Ceftazidime/Avibactam versus Polymyxin B in the Challenge of Carbapenem-Resistant Pseudomonas aeruginosa Infection
por: Chen, Juan, et al.
Publicado: (2022)

Successful treatment of extensively drug-resistant Acinetobacter baumannii ventriculitis with polymyxin B and tigecycline- a case report
por: Guo, Wei, et al.
Publicado: (2018)

Optimization of polymyxin B regimens for the treatment of carbapenem-resistant organism nosocomial pneumonia: a real-world prospective study
por: Tang, Tiantian, et al.
Publicado: (2023)

BL02, a phage against carbapenem- and polymyxin-B resistant Klebsiella pneumoniae, isolated from sewage: A preclinical study
por: Liang, Zhen, et al.
Publicado: (2023)

Efficacy of polymyxins in the treatment of carbapenem-resistant Enterobacteriaceae infections: a systematic review and meta-analysis
por: Ni, Wentao, et al.
Publicado: (2015)

In vitro and in vivo Activity of Combinations of Polymyxin B with Other Antimicrobials Against Carbapenem-Resistant Acinetobacter baumannii
por: Zhang, Hui, et al.
Publicado: (2021)

Hetero- and adaptive resistance to polymyxin B in OXA-23-producing carbapenem-resistant Acinetobacter baumannii isolates
por: Barin, Juliana, et al.
Publicado: (2013)

Therapeutic Drug Monitoring of Ceftazidime-Avibactam Concentrations in Carbapenem-Resistant K. pneumoniae-Infected Patients With Different Kidney Statuses
por: Teng, Xin-Qi, et al.
Publicado: (2022)

2262. Ceftazidime–Avibactam vs. Polymyxin B in the Treatment of Infections Due to Carbapenem-Resistant Enterobacteriaceae
por: John, Jamie, et al.
Publicado: (2019)

Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
por: Abboud, Cely Saad, et al.
Publicado: (2017)

Early use of polymyxin B reduces the mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection
por: Liang, Qiqiang, et al.
Publicado: (2019)

Polymyxin B therapy based on therapeutic drug monitoring in carbapenem-resistant organisms sepsis: the PMB-CROS randomized clinical trial
por: Liu, Shaohua, et al.
Publicado: (2023)

Effectiveness and Nephrotoxicity of Intravenous Polymyxin B in Carbapenem-Resistant Gram-Negative Bacterial Infections Among Chinese Children
por: Jia, Xuedong, et al.
Publicado: (2022)

Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil
por: Rodrigues, Ana Claudia Souza, et al.
Publicado: (2019)

2451. Synergistic Activity of Ceftazidime–Avibactam in Combination With Polymyxin B Against Carbapenem-Resistant Klebsiella pneumoniae
por: Borjan, Jovan, et al.
Publicado: (2018)

Polymyxin for treatment of ventilator-associated pneumonia in a setting of high carbapenem resistance
por: Bento Talizin, Thalita, et al.
Publicado: (2020)

Clinical efficacy and safety of polymyxins based versus non-polymyxins based therapies in the infections caused by carbapenem-resistant Acinetobacter baumannii: a systematic review and meta-analysis
por: Lyu, Cheng, et al.
Publicado: (2020)

Treatment of Carbapenem-Resistant Multidrug-Resistant Gram-Negative Bacilli with Intracerebroventricular Injection of Polymyxin B: A Retrospective Study
por: Liu, Dongsheng, et al.
Publicado: (2022)

In-Vitro Activity of Polymyxin B, Rifampicin, Tigecycline Alone and in Combination against Carbapenem-Resistant Acinetobacter baumannii in Singapore
por: Lim, Tze-Peng, et al.
Publicado: (2011)

In vitro and in vivo Activity of Combinations of Polymyxin B with Other Antimicrobials Against Carbapenem-Resistant Acinetobacter baumannii [Corrigendum]
Publicado: (2021)

Evaluation of polymyxin B AUC/MIC ratio for dose optimization in patients with carbapenem-resistant Klebsiella pneumoniae infection
por: Wang, Peile, et al.
Publicado: (2023)

2815. Outcomes of Novel Antimicrobials Compared to Polymyxin B for treatment of infections due Carbapenem-Resistant Enterobacterales Infections
por: Zheng, Tina, et al.
Publicado: (2023)

Combatting Planktonic and Biofilm Populations of Carbapenem-Resistant Acinetobacter baumannii with Polymyxin-Based Combinations
por: Wences, Marisol, et al.
Publicado: (2022)

Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa
por: Venne, Danielle M., et al.
Publicado: (2023)

Analysis of a Refractory Case of Pediatric Meningitis Caused by Klebsiella pneumoniae Co-Resistant to Carbapenems and Polymyxins
por: Huang, Xu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hfjcibcen5i98gg95e9auiiu59