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Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network

Background: Alzheimer’s disease is a type of dementia denoted by progressive neuronal death due to the accumulation of proteinaceous aggregates of Tau. Post-translational modifications like hyperphosphorylation, truncation, glycation, etc. play a pivotal role in Tau pathogenesis. Glycation of Tau ai...

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Detalles Bibliográficos
Autores principales: Sonawane, Shweta Kishor, Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169072/
https://www.ncbi.nlm.nih.gov/pubmed/34084282
http://dx.doi.org/10.18632/oncotarget.27963