Cargando…
Anticipation of temporally structured events in the brain
Learning about temporal structure is adaptive because it enables the generation of expectations. We examined how the brain uses experience in structured environments to anticipate upcoming events. During fMRI (functional magnetic resonance imaging), individuals watched a 90 s movie clip six times. U...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169103/ https://www.ncbi.nlm.nih.gov/pubmed/33884953 http://dx.doi.org/10.7554/eLife.64972 |
_version_ | 1783701991350861824 |
---|---|
author | Lee, Caroline S Aly, Mariam Baldassano, Christopher |
author_facet | Lee, Caroline S Aly, Mariam Baldassano, Christopher |
author_sort | Lee, Caroline S |
collection | PubMed |
description | Learning about temporal structure is adaptive because it enables the generation of expectations. We examined how the brain uses experience in structured environments to anticipate upcoming events. During fMRI (functional magnetic resonance imaging), individuals watched a 90 s movie clip six times. Using a hidden Markov model applied to searchlights across the whole brain, we identified temporal shifts between activity patterns evoked by the first vs. repeated viewings of the movie clip. In many regions throughout the cortex, neural activity patterns for repeated viewings shifted to precede those of initial viewing by up to 15 s. This anticipation varied hierarchically in a posterior (less anticipation) to anterior (more anticipation) fashion. We also identified specific regions in which the timing of the brain’s event boundaries was related to those of human-labeled event boundaries, with the timing of this relationship shifting on repeated viewings. With repeated viewing, the brain’s event boundaries came to precede human-annotated boundaries by 1–4 s on average. Together, these results demonstrate a hierarchy of anticipatory signals in the human brain and link them to subjective experiences of events. |
format | Online Article Text |
id | pubmed-8169103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-81691032021-06-04 Anticipation of temporally structured events in the brain Lee, Caroline S Aly, Mariam Baldassano, Christopher eLife Neuroscience Learning about temporal structure is adaptive because it enables the generation of expectations. We examined how the brain uses experience in structured environments to anticipate upcoming events. During fMRI (functional magnetic resonance imaging), individuals watched a 90 s movie clip six times. Using a hidden Markov model applied to searchlights across the whole brain, we identified temporal shifts between activity patterns evoked by the first vs. repeated viewings of the movie clip. In many regions throughout the cortex, neural activity patterns for repeated viewings shifted to precede those of initial viewing by up to 15 s. This anticipation varied hierarchically in a posterior (less anticipation) to anterior (more anticipation) fashion. We also identified specific regions in which the timing of the brain’s event boundaries was related to those of human-labeled event boundaries, with the timing of this relationship shifting on repeated viewings. With repeated viewing, the brain’s event boundaries came to precede human-annotated boundaries by 1–4 s on average. Together, these results demonstrate a hierarchy of anticipatory signals in the human brain and link them to subjective experiences of events. eLife Sciences Publications, Ltd 2021-04-22 /pmc/articles/PMC8169103/ /pubmed/33884953 http://dx.doi.org/10.7554/eLife.64972 Text en © 2021, Lee et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Lee, Caroline S Aly, Mariam Baldassano, Christopher Anticipation of temporally structured events in the brain |
title | Anticipation of temporally structured events in the brain |
title_full | Anticipation of temporally structured events in the brain |
title_fullStr | Anticipation of temporally structured events in the brain |
title_full_unstemmed | Anticipation of temporally structured events in the brain |
title_short | Anticipation of temporally structured events in the brain |
title_sort | anticipation of temporally structured events in the brain |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169103/ https://www.ncbi.nlm.nih.gov/pubmed/33884953 http://dx.doi.org/10.7554/eLife.64972 |
work_keys_str_mv | AT leecarolines anticipationoftemporallystructuredeventsinthebrain AT alymariam anticipationoftemporallystructuredeventsinthebrain AT baldassanochristopher anticipationoftemporallystructuredeventsinthebrain |