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Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience

BACKGROUND: The aim of this study was to evaluate the usefulness of a novel clinical score — the InterTAK Diagnostic Score in differentiating Takotsubo syndrome (TTS) from acute coronary syndrome (ACS). METHODS: Medical records of 40 consecutive patients with ACS and 20 patients with TTS were manage...

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Autores principales: Samul-Jastrzębska, Judyta, Roik, Marek, Wretowski, Dominik, Łabyk, Andrzej, Ślubowska, Antonina, Bizoń, Anna, Paczyńska, Marzanna, Kurnicka, Katarzyna, Pruszczyk, Piotr, Ciurzyński, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169192/
https://www.ncbi.nlm.nih.gov/pubmed/31489610
http://dx.doi.org/10.5603/CJ.a2019.0086
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author Samul-Jastrzębska, Judyta
Roik, Marek
Wretowski, Dominik
Łabyk, Andrzej
Ślubowska, Antonina
Bizoń, Anna
Paczyńska, Marzanna
Kurnicka, Katarzyna
Pruszczyk, Piotr
Ciurzyński, Michał
author_facet Samul-Jastrzębska, Judyta
Roik, Marek
Wretowski, Dominik
Łabyk, Andrzej
Ślubowska, Antonina
Bizoń, Anna
Paczyńska, Marzanna
Kurnicka, Katarzyna
Pruszczyk, Piotr
Ciurzyński, Michał
author_sort Samul-Jastrzębska, Judyta
collection PubMed
description BACKGROUND: The aim of this study was to evaluate the usefulness of a novel clinical score — the InterTAK Diagnostic Score in differentiating Takotsubo syndrome (TTS) from acute coronary syndrome (ACS). METHODS: Medical records of 40 consecutive patients with ACS and 20 patients with TTS were managed and retrospectively analyzed at the documented center. Each patient was evaluated using the Inter-TAK Diagnostic Score. To illustrate the diagnostic ability of the score, a receiver operating characteristic (ROC) curve was performed. RESULTS: Takotsube syndrome patients were more often female compared to the ACS group (70% vs. 27.5%, p = 0.002), an emotional trigger was more prevalent among the TTS group (65% vs. 7.5%, p < 0.001). The area under the curve (AUC) for the score was 0.885 (95% confidence interval [CI] 0.78–0.97). Using a cut-off value of 45 points, the sum of sensitivity and specificity was the highest. However, when patients with a score of ≥ 50 were diagnosed as TTS, 85% were diagnosed correctly. When patients with score ≤ 31 were diagnosed as ACS, 92% were diagnosed correctly. CONCLUSIONS: The InterTAK Diagnostic Score might help in differentiating TTS from ACSs with high sensitivity and specificity. This finding requires further investigation to confirm its clinical utility.
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spelling pubmed-81691922021-06-02 Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience Samul-Jastrzębska, Judyta Roik, Marek Wretowski, Dominik Łabyk, Andrzej Ślubowska, Antonina Bizoń, Anna Paczyńska, Marzanna Kurnicka, Katarzyna Pruszczyk, Piotr Ciurzyński, Michał Cardiol J Clinical Cardiology BACKGROUND: The aim of this study was to evaluate the usefulness of a novel clinical score — the InterTAK Diagnostic Score in differentiating Takotsubo syndrome (TTS) from acute coronary syndrome (ACS). METHODS: Medical records of 40 consecutive patients with ACS and 20 patients with TTS were managed and retrospectively analyzed at the documented center. Each patient was evaluated using the Inter-TAK Diagnostic Score. To illustrate the diagnostic ability of the score, a receiver operating characteristic (ROC) curve was performed. RESULTS: Takotsube syndrome patients were more often female compared to the ACS group (70% vs. 27.5%, p = 0.002), an emotional trigger was more prevalent among the TTS group (65% vs. 7.5%, p < 0.001). The area under the curve (AUC) for the score was 0.885 (95% confidence interval [CI] 0.78–0.97). Using a cut-off value of 45 points, the sum of sensitivity and specificity was the highest. However, when patients with a score of ≥ 50 were diagnosed as TTS, 85% were diagnosed correctly. When patients with score ≤ 31 were diagnosed as ACS, 92% were diagnosed correctly. CONCLUSIONS: The InterTAK Diagnostic Score might help in differentiating TTS from ACSs with high sensitivity and specificity. This finding requires further investigation to confirm its clinical utility. Via Medica 2021-05-25 /pmc/articles/PMC8169192/ /pubmed/31489610 http://dx.doi.org/10.5603/CJ.a2019.0086 Text en Copyright © 2021 Via Medica https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
spellingShingle Clinical Cardiology
Samul-Jastrzębska, Judyta
Roik, Marek
Wretowski, Dominik
Łabyk, Andrzej
Ślubowska, Antonina
Bizoń, Anna
Paczyńska, Marzanna
Kurnicka, Katarzyna
Pruszczyk, Piotr
Ciurzyński, Michał
Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience
title Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience
title_full Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience
title_fullStr Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience
title_full_unstemmed Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience
title_short Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience
title_sort evaluation of the intertak diagnostic score in differentiating takotsubo syndrome from acute coronary syndrome. a single center experience
topic Clinical Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169192/
https://www.ncbi.nlm.nih.gov/pubmed/31489610
http://dx.doi.org/10.5603/CJ.a2019.0086
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