Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation

Smoothened is a key receptor of the hedgehog pathway, but the roles of Smoothened in cardiac development remain incompletely understood. In this study, we found that the conditional knockout of Smoothened from the mesoderm impaired the development of the venous pole of the heart and resulted in hypo...

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Detalles Bibliográficos
Autores principales: Zhang, Chaohui, Li, Yuxin, Cao, Jiaheng, Yu, Beibei, Zhang, Kaiyue, Li, Ke, Xu, Xinhui, Guo, Zhikun, Liang, Yinming, Yang, Xiao, Yang, Zhongzhou, Sun, Yunfu, Kaartinen, Vesa, Ding, Keyue, Wang, Jikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169207/
https://www.ncbi.nlm.nih.gov/pubmed/34062094
http://dx.doi.org/10.1098/rsob.210020

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