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Neuropilin-1 assists SARS-CoV-2 infection by stimulating the separation of Spike protein S1 and S2

The cell surface receptor Neuropilin-1 (Nrp1) was recently identified as a host factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry. The Spike protein of SARS-CoV-2 is cleaved into two segments, the S1 (residues (res.) 1–685) and the S2 (res. 686–1273) domains by furin prot...

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Detalles Bibliográficos
Autores principales: Li, Zhen-lu, Buck, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169233/
https://www.ncbi.nlm.nih.gov/pubmed/34087218
http://dx.doi.org/10.1016/j.bpj.2021.05.026

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