Cargando…
Neuropilin-1 assists SARS-CoV-2 infection by stimulating the separation of Spike protein S1 and S2
The cell surface receptor Neuropilin-1 (Nrp1) was recently identified as a host factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry. The Spike protein of SARS-CoV-2 is cleaved into two segments, the S1 (residues (res.) 1–685) and the S2 (res. 686–1273) domains by furin prot...
Autores principales: | Li, Zhen-lu, Buck, Matthias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169233/ https://www.ncbi.nlm.nih.gov/pubmed/34087218 http://dx.doi.org/10.1016/j.bpj.2021.05.026 |
Ejemplares similares
-
Neuropilin-1 Assists SARS-CoV-2 Infection by Stimulating the Separation of Spike Protein Domains S1 and S2
por: Li, Zhen-lu, et al.
Publicado: (2021) -
Computational analysis of interior mutations of SARS-CoV-2 Spike protein suggest a balance of protein stability and S2: S1 separation propensity
por: Li, Zhen-lu, et al.
Publicado: (2022) -
Novel Small-Molecule Inhibitors of the SARS-CoV-2 Spike Protein Binding to Neuropilin 1
por: Kolarič, Anja, et al.
Publicado: (2022) -
SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia
por: Moutal, Aubin, et al.
Publicado: (2020) -
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia
por: Moutal, Aubin, et al.
Publicado: (2021)