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Enhanced sampling protocol to elucidate fusion peptide opening of SARS-CoV-2 spike protein

Large-scale conformational transitions in the spike protein S2 domain are required during host-cell infection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Although conventional molecular dynamics simulations have been extensively used to study therapeutic targets of SAR...

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Detalles Bibliográficos
Autores principales:	Remington, Jacob M., McKay, Kyle T., Ferrell, Jonathon B., Schneebeli, Severin T., Li, Jianing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169235/ https://www.ncbi.nlm.nih.gov/pubmed/34087207 http://dx.doi.org/10.1016/j.bpj.2021.05.022

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