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D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution

Coronavirus Disease 2019 (COVID-19) has become one of the most urgent public health events worldwide due to its high infectivity and mortality. Computed tomography (CT) is a significant screening tool for COVID-19 infection, and automatic segmentation of lung infection in COVID-19 CT images can assi...

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Autores principales: Zhao, Xiangyu, Zhang, Peng, Song, Fan, Fan, Guangda, Sun, Yangyang, Wang, Yujia, Tian, Zheyuan, Zhang, Luqi, Zhang, Guanglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169238/
https://www.ncbi.nlm.nih.gov/pubmed/34146799
http://dx.doi.org/10.1016/j.compbiomed.2021.104526
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author Zhao, Xiangyu
Zhang, Peng
Song, Fan
Fan, Guangda
Sun, Yangyang
Wang, Yujia
Tian, Zheyuan
Zhang, Luqi
Zhang, Guanglei
author_facet Zhao, Xiangyu
Zhang, Peng
Song, Fan
Fan, Guangda
Sun, Yangyang
Wang, Yujia
Tian, Zheyuan
Zhang, Luqi
Zhang, Guanglei
author_sort Zhao, Xiangyu
collection PubMed
description Coronavirus Disease 2019 (COVID-19) has become one of the most urgent public health events worldwide due to its high infectivity and mortality. Computed tomography (CT) is a significant screening tool for COVID-19 infection, and automatic segmentation of lung infection in COVID-19 CT images can assist diagnosis and health care of patients. However, accurate and automatic segmentation of COVID-19 lung infections is faced with a few challenges, including blurred edges of infection and relatively low sensitivity. To address the issues above, a novel dilated dual attention U-Net based on the dual attention strategy and hybrid dilated convolutions, namely D2A U-Net, is proposed for COVID-19 lesion segmentation in CT slices. In our D2A U-Net, the dual attention strategy composed of two attention modules is utilized to refine feature maps and reduce the semantic gap between different levels of feature maps. Moreover, the hybrid dilated convolutions are introduced to the model decoder to achieve larger receptive fields, which refines the decoding process. The proposed method is evaluated on an open-source dataset and achieves a Dice score of 0.7298 and recall score of 0.7071, which outperforms the popular cutting-edge methods in the semantic segmentation. The proposed network is expected to be a potential AI-based approach used for the diagnosis and prognosis of COVID-19 patients.
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spelling pubmed-81692382021-06-02 D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution Zhao, Xiangyu Zhang, Peng Song, Fan Fan, Guangda Sun, Yangyang Wang, Yujia Tian, Zheyuan Zhang, Luqi Zhang, Guanglei Comput Biol Med Article Coronavirus Disease 2019 (COVID-19) has become one of the most urgent public health events worldwide due to its high infectivity and mortality. Computed tomography (CT) is a significant screening tool for COVID-19 infection, and automatic segmentation of lung infection in COVID-19 CT images can assist diagnosis and health care of patients. However, accurate and automatic segmentation of COVID-19 lung infections is faced with a few challenges, including blurred edges of infection and relatively low sensitivity. To address the issues above, a novel dilated dual attention U-Net based on the dual attention strategy and hybrid dilated convolutions, namely D2A U-Net, is proposed for COVID-19 lesion segmentation in CT slices. In our D2A U-Net, the dual attention strategy composed of two attention modules is utilized to refine feature maps and reduce the semantic gap between different levels of feature maps. Moreover, the hybrid dilated convolutions are introduced to the model decoder to achieve larger receptive fields, which refines the decoding process. The proposed method is evaluated on an open-source dataset and achieves a Dice score of 0.7298 and recall score of 0.7071, which outperforms the popular cutting-edge methods in the semantic segmentation. The proposed network is expected to be a potential AI-based approach used for the diagnosis and prognosis of COVID-19 patients. Elsevier Ltd. 2021-08 2021-06-02 /pmc/articles/PMC8169238/ /pubmed/34146799 http://dx.doi.org/10.1016/j.compbiomed.2021.104526 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zhao, Xiangyu
Zhang, Peng
Song, Fan
Fan, Guangda
Sun, Yangyang
Wang, Yujia
Tian, Zheyuan
Zhang, Luqi
Zhang, Guanglei
D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution
title D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution
title_full D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution
title_fullStr D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution
title_full_unstemmed D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution
title_short D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution
title_sort d2a u-net: automatic segmentation of covid-19 ct slices based on dual attention and hybrid dilated convolution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169238/
https://www.ncbi.nlm.nih.gov/pubmed/34146799
http://dx.doi.org/10.1016/j.compbiomed.2021.104526
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