The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors

The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs)...

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Autores principales: Tu, Jiajie, Yang, Huan, Jiang, Lei, Chen, Yu, Yu Chen, Li, Zhe, Li, Lei, Zhang, Yuanyuan, Chen, Xiaochun, Chen, He, Yu, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169271/
https://www.ncbi.nlm.nih.gov/pubmed/34122542
http://dx.doi.org/10.1155/2021/5572063
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author Tu, Jiajie
Yang, Huan
Jiang, Lei
Chen, Yu
Yu Chen,
Li, Zhe
Li, Lei
Zhang, Yuanyuan
Chen, Xiaochun
Chen, He
Yu, Zhiying
author_facet Tu, Jiajie
Yang, Huan
Jiang, Lei
Chen, Yu
Yu Chen,
Li, Zhe
Li, Lei
Zhang, Yuanyuan
Chen, Xiaochun
Chen, He
Yu, Zhiying
author_sort Tu, Jiajie
collection PubMed
description The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. This review systematically summarizes the role of ncRNAs in estrogen-dependent tumors and common patterns of regulatory mechanisms to explore their future research directions in tumor diagnosis, treatment, and prognosis. This may provide new ideas for the potential application of ncRNAs in estrogen-dependent female reproductive system tumors.
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spelling pubmed-81692712021-06-11 The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors Tu, Jiajie Yang, Huan Jiang, Lei Chen, Yu Yu Chen, Li, Zhe Li, Lei Zhang, Yuanyuan Chen, Xiaochun Chen, He Yu, Zhiying Int J Endocrinol Review Article The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. This review systematically summarizes the role of ncRNAs in estrogen-dependent tumors and common patterns of regulatory mechanisms to explore their future research directions in tumor diagnosis, treatment, and prognosis. This may provide new ideas for the potential application of ncRNAs in estrogen-dependent female reproductive system tumors. Hindawi 2021-05-24 /pmc/articles/PMC8169271/ /pubmed/34122542 http://dx.doi.org/10.1155/2021/5572063 Text en Copyright © 2021 Jiajie Tu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tu, Jiajie
Yang, Huan
Jiang, Lei
Chen, Yu
Yu Chen,
Li, Zhe
Li, Lei
Zhang, Yuanyuan
Chen, Xiaochun
Chen, He
Yu, Zhiying
The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
title The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
title_full The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
title_fullStr The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
title_full_unstemmed The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
title_short The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors
title_sort central roles of noncoding rna in estrogen-dependent female reproductive system tumors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169271/
https://www.ncbi.nlm.nih.gov/pubmed/34122542
http://dx.doi.org/10.1155/2021/5572063
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