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Erfolgreiche Behandlung einer chronischen Prurigo mit Dupilumab

Chronic prurigo is characterized by persistent itching und partly accompanied by secondary skin excoriation. Diagnostic evaluation is of special relevance and atopic diathesis is a frequent pathogenic factor. We present a patient with prurigo of multifactorial etiology (atopic diathesis, impaired ki...

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Detalles Bibliográficos
Autores principales: Winkler, Julia K., Haenssle, Holger A., Enk, Alexander, Toberer, Ferdinand, Hartmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169508/
https://www.ncbi.nlm.nih.gov/pubmed/33180178
http://dx.doi.org/10.1007/s00105-020-04721-0
Descripción
Sumario:Chronic prurigo is characterized by persistent itching und partly accompanied by secondary skin excoriation. Diagnostic evaluation is of special relevance and atopic diathesis is a frequent pathogenic factor. We present a patient with prurigo of multifactorial etiology (atopic diathesis, impaired kidney function, diabetes and polyneuropathy). After several unsuccessful prior treatment approaches, the patient was treated with dupilumab, which resulted in a tremendous improvement of itching, skin lesions, and quality of life.