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Cascaded processing enables continuous upstream processing with E. coli BL21(DE3)
In many industrial sectors continuous processing is already the golden standard to maximize productivity. However, when working with living cells, subpopulation formation causes instabilities in long-term cultivations. In cascaded continuous cultivation, biomass formation and recombinant protein exp...
Autores principales: | Kittler, Stefan, Slouka, Christoph, Pell, Andreas, Lamplot, Roman, Besleaga, Mihail, Ablasser, Sarah, Herwig, Christoph, Spadiut, Oliver, Kopp, Julian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169658/ https://www.ncbi.nlm.nih.gov/pubmed/34075099 http://dx.doi.org/10.1038/s41598-021-90899-9 |
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