Drug screening with zebrafish visual behavior identifies carvedilol as a potential treatment for an autosomal dominant form of retinitis pigmentosa

Retinitis Pigmentosa (RP) is a mostly incurable inherited retinal degeneration affecting approximately 1 in 4000 individuals globally. The goal of this work was to identify drugs that can help patients suffering from the disease. To accomplish this, we screened drugs on a zebrafish autosomal dominan...

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Detalles Bibliográficos
Autores principales: Ganzen, Logan, Ko, Mee Jung, Zhang, Mengrui, Xie, Rui, Chen, Yongkai, Zhang, Liyun, James, Rebecca, Mumm, Jeff, van Rijn, Richard M., Zhong, Wenxuan, Pang, Chi Pui, Zhang, Mingzhi, Tsujikawa, Motokazu, Leung, Yuk Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169685/
https://www.ncbi.nlm.nih.gov/pubmed/34075074
http://dx.doi.org/10.1038/s41598-021-89482-z

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