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Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population

Population aging is likely increasing the number of surgically treated very old (≥ 80–year-old) intracranial meningioma (IM) patients. Since there is little data on mortality in this patient group, we studied whether survival of surgically treated very old IM patients differs from survival of a matc...

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Autores principales: Rautalin, Ilari, Schwartz, Christoph, Niemelä, Mika, Korja, Miikka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169827/
https://www.ncbi.nlm.nih.gov/pubmed/34075085
http://dx.doi.org/10.1038/s41598-021-90842-y
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author Rautalin, Ilari
Schwartz, Christoph
Niemelä, Mika
Korja, Miikka
author_facet Rautalin, Ilari
Schwartz, Christoph
Niemelä, Mika
Korja, Miikka
author_sort Rautalin, Ilari
collection PubMed
description Population aging is likely increasing the number of surgically treated very old (≥ 80–year-old) intracranial meningioma (IM) patients. Since there is little data on mortality in this patient group, we studied whether survival of surgically treated very old IM patients differs from survival of a matched general population. We retrospectively identified 83 consecutive very old IM patients (median age 83 years; 69% women) operated between 2010 and 2018. During the first postoperative year, operated IM patients suffered 2.5 times higher mortality as compared to age- and sex-matched general population but no annual survival difference occurred thereafter. Regarding cumulative estimates, no excess mortality was detected after the second postoperative year. Of the patient who were and who were not able to live at home preoperatively, 78% and 42% lived at home within 3 months, respectively. Preoperative loss of capability to live at home associated with a less frequent return to home [odds ratio (95% confidence interval) 0.21 (0.06–0.67)]. Operated very old IM patients had short-term excess mortality but similar cumulative survival as the matched general population. Moreover, most patients returned home soon after surgery.
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spelling pubmed-81698272021-06-02 Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population Rautalin, Ilari Schwartz, Christoph Niemelä, Mika Korja, Miikka Sci Rep Article Population aging is likely increasing the number of surgically treated very old (≥ 80–year-old) intracranial meningioma (IM) patients. Since there is little data on mortality in this patient group, we studied whether survival of surgically treated very old IM patients differs from survival of a matched general population. We retrospectively identified 83 consecutive very old IM patients (median age 83 years; 69% women) operated between 2010 and 2018. During the first postoperative year, operated IM patients suffered 2.5 times higher mortality as compared to age- and sex-matched general population but no annual survival difference occurred thereafter. Regarding cumulative estimates, no excess mortality was detected after the second postoperative year. Of the patient who were and who were not able to live at home preoperatively, 78% and 42% lived at home within 3 months, respectively. Preoperative loss of capability to live at home associated with a less frequent return to home [odds ratio (95% confidence interval) 0.21 (0.06–0.67)]. Operated very old IM patients had short-term excess mortality but similar cumulative survival as the matched general population. Moreover, most patients returned home soon after surgery. Nature Publishing Group UK 2021-06-01 /pmc/articles/PMC8169827/ /pubmed/34075085 http://dx.doi.org/10.1038/s41598-021-90842-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Rautalin, Ilari
Schwartz, Christoph
Niemelä, Mika
Korja, Miikka
Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
title Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
title_full Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
title_fullStr Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
title_full_unstemmed Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
title_short Mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
title_sort mortality of surgically treated 80-year-old or older intracranial meningioma patients in comparison to matched general population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169827/
https://www.ncbi.nlm.nih.gov/pubmed/34075085
http://dx.doi.org/10.1038/s41598-021-90842-y
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