IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R

Metastasis is the major reason for the high mortality of colorectal cancer (CRC) patients and its molecular mechanism remains unclear. Here, we report a novel role of Homeobox A13 (HOXA13), a member of the Homeobox (HOX) family, in promoting CRC metastasis. The elevated expression of HOXA13 was posi...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiao, Chenyang, Huang, Wenjie, Chen, Jie, Feng, Weibo, Zhang, Tongyue, Wang, Yijun, Liu, Danfei, Ji, Xiaoyu, Xie, Meng, Sun, Mengyu, Fan, Daiming, Wu, Kaichun, Xia, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169856/
https://www.ncbi.nlm.nih.gov/pubmed/34075028
http://dx.doi.org/10.1038/s41419-021-03833-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169856/
https://www.ncbi.nlm.nih.gov/pubmed/34075028
http://dx.doi.org/10.1038/s41419-021-03833-2

Ejemplares similares