Cargando…

Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study

This study aims to investigate the characteristics of the phenotype and management of chronic obstructive pulmonary disease (COPD) patients in the general population in China. We analyzed spirometry-confirmed COPD patients who were identified from a population-based, nationally representative sample...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Heling, Jia, Guohua, Cong, Shu, Sun, Wanlu, Fan, Jing, Wang, Ning, Feng, Yajing, Wang, Baohua, Curtis, Jeffrey L., Wang, Linhong, Fang, Liwen, Chen, Yahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169915/
https://www.ncbi.nlm.nih.gov/pubmed/34075048
http://dx.doi.org/10.1038/s41533-021-00243-x
Descripción
Sumario:This study aims to investigate the characteristics of the phenotype and management of chronic obstructive pulmonary disease (COPD) patients in the general population in China. We analyzed spirometry-confirmed COPD patients who were identified from a population-based, nationally representative sample in China. All participants were measured with airflow limitation severity based on post-bronchodilator FEV(1) percent predicted, bronchodilator responsiveness, exacerbation history, and respiratory symptoms. Among a total of 9134 COPD patients, 90.3% were non-exacerbators, 2.9% were frequent exacerbators without chronic bronchitis, 2.0% were frequent exacerbators with chronic bronchitis, and 4.8% were asthma-COPD overlap. Less than 5% of non-exacerbators ever had pulmonary function testing performed. The utilization rate of inhaled medication in non-exacerbators, exacerbators without chronic bronchitis, exacerbators with chronic bronchitis, and asthma-COPD overlap was 1.4, 23.5, 29.5, and 19.4%, respectively. A comprehensive strategy for the management of COPD patients based on phenotype in primary care is urgently needed.