Diverse meibum lipids produced by Awat1 and Awat2 are important for stabilizing tear film and protecting the ocular surface

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A lipid layer consisting of meibum lipids exists in the tear film and functions in preventing dry eye disease. Although the meibum lipids include diverse lipid classes, the synthesis pathway and role of each class remain largely unknown. Here, we created single and double knockout (KO and DKO, respe...

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Detalles Bibliográficos
Autores principales: Sawai, Megumi, Watanabe, Keisuke, Tanaka, Kana, Kinoshita, Wataru, Otsuka, Kento, Miyamoto, Masatoshi, Sassa, Takayuki, Kihara, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169949/
https://www.ncbi.nlm.nih.gov/pubmed/34113821
http://dx.doi.org/10.1016/j.isci.2021.102478

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