SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury

Hepatic stellate cells (HSCs) are crucial for liver injury repair and cirrhosis. However, the mechanism of chemotactic recruitment of HSCs into injury loci is still largely unknown. Here, we demonstrate that serum amyloid A1 (SAA1) acts as a chemokine recruiting HSCs toward injury loci signaling via...

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Detalles Bibliográficos
Autores principales: Getachew, Anteneh, Abbas, Nasir, You, Kai, Yang, Zhen, Hussain, Muzammal, Huang, Xinping, Cheng, Ziqi, Tan, Shenglin, Tao, Jiawang, Yu, Xiaorui, Chen, Yan, Yang, Fan, Pan, Tingcai, Xu, Yingying, Xu, Guosheng, Zhuang, Yuanqi, Wu, FeiMa, Li, Yinxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169952/
https://www.ncbi.nlm.nih.gov/pubmed/34113824
http://dx.doi.org/10.1016/j.isci.2021.102483

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