Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

Colorectal cancer (CRC) progression is a complex process that is not well understood. We describe an in vitro organ-on-chip model that emulates in vivo tissue structure and the tumor microenvironment (TME) to better understand intravasation, an early step in metastasis. The CRC-on-chip incorporates...

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Detalles Bibliográficos
Autores principales: Strelez, Carly, Chilakala, Sujatha, Ghaffarian, Kimya, Lau, Roy, Spiller, Erin, Ung, Nolan, Hixon, Danielle, Yoon, Ah Young, Sun, Ren X., Lenz, Heinz-Josef, Katz, Jonathan E., Mumenthaler, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169959/
https://www.ncbi.nlm.nih.gov/pubmed/34113836
http://dx.doi.org/10.1016/j.isci.2021.102509

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