Cargando…

Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2

The RLRs play critical roles in sensing and fighting viral infections especially RNA virus infections. Despite the extensive studies on RLRs in humans and mice, there is a lack of systemic investigation of livestock animal RLRs. In this study, we characterized the porcine RLR members RIG-I, MDA5 and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shuangjie, Yang, Jie, Zhu, Yuanyuan, Wang, Hui, Ji, Xingyu, Luo, Jia, Shao, Qi, Xu, Yulin, Liu, Xueliang, Zheng, Wanglong, Meurens, François, Chen, Nanhua, Zhu, Jianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169967/ https://www.ncbi.nlm.nih.gov/pubmed/34093517 http://dx.doi.org/10.3389/fimmu.2021.609543

Ejemplares similares

Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses
por: Li, Shuangjie, et al.
Publicado: (2021)

Development of Specific Monoclonal Antibodies against Porcine RIG-I-like Receptors Revealed the Species Specificity
por: Shao, Qi, et al.
Publicado: (2023)

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5
por: Brisse, Morgan, et al.
Publicado: (2019)

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5
por: Reikine, Stephanie, et al.
Publicado: (2014)

Duck LGP2 Downregulates RIG-I Signaling Pathway-Mediated Innate Immunity Against Tembusu Virus
por: Li, Tianxu, et al.
Publicado: (2022)

Porcine IFI16 Negatively Regulates cGAS Signaling Through the Restriction of DNA Binding and Stimulation
por: Zheng, Wanglong, et al.
Publicado: (2020)

The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA
por: Pippig, Diana A., et al.
Publicado: (2009)

Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2
por: Zhang, Yuqiang, et al.
Publicado: (2021)

Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells
por: Takahashi, Tomoko, et al.
Publicado: (2018)

Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination
por: Tanaka, Yukie, et al.
Publicado: (2022)

RNA sensing via the RIG‐I‐like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency
por: Stok, Jorn E, et al.
Publicado: (2022)

Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation
por: He, Felix B., et al.
Publicado: (2022)

Comparative analysis of viral RNA signatures on different RIG-I-like receptors
por: Sanchez David, Raul Y, et al.
Publicado: (2016)

Editorial: Updates on RIG-I-like receptor-mediated innate immune responses
por: Kishore, Uday, et al.
Publicado: (2023)

Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis
por: Xia, Nengwen, et al.
Publicado: (2022)

Friend or foe: RIG- I like receptors and diseases
por: Song, Jie, et al.
Publicado: (2022)

Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling
por: Guo, Guijie, et al.
Publicado: (2021)

Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity
por: Liu, Yiliu, et al.
Publicado: (2017)

Regulation of RIG-I Activation by K63-Linked Polyubiquitination
por: Okamoto, Masaaki, et al.
Publicado: (2018)

Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease
por: Wang, Hao, et al.
Publicado: (2022)

The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5
por: Bu, Lang, et al.
Publicado: (2020)

In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells
por: Runge, Simon, et al.
Publicado: (2014)

Therapeutic Targeting of RIG-I and MDA5 Might Not Lead to the Same Rome
por: Kasumba, Dacquin M., et al.
Publicado: (2019)

Tumor suppressor activity of RIG-I
por: Li, Xian-Yang, et al.
Publicado: (2014)

The RIG‐I‐like receptor LGP2 inhibits Dicer‐dependent processing of long double‐stranded RNA and blocks RNA interference in mammalian cells
por: van der Veen, Annemarthe G, et al.
Publicado: (2018)

CD163-Expressing Porcine Macrophages Support NADC30-like and NADC34-like PRRSV Infections
por: Xu, Yulin, et al.
Publicado: (2022)

RIG-I and MDA5 Protect Mice From Pichinde Virus Infection by Controlling Viral Replication and Regulating Immune Responses to the Infection
por: Brisse, Morgan, et al.
Publicado: (2021)

Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination
por: Likai, Ji, et al.
Publicado: (2019)

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization
por: Wang, Wenshuai, et al.
Publicado: (2023)

Functional Evolution of Avian RIG-I-Like Receptors
por: Zheng, Wanjing, et al.
Publicado: (2018)

Disturbance of cytoskeleton primes RIG-I-like receptors
por: Bordon, Yvonne
Publicado: (2022)

Advances in aquatic animal RIG-I-like receptors
por: Liang, Bo, et al.
Publicado: (2021)

Replication of Porcine Astrovirus Type 1-Infected PK-15 Cells In Vitro Affected by RIG-I and MDA5 Signaling Pathways
por: Dong, Qinting, et al.
Publicado: (2023)

Factors affecting RIG-I-Like receptors activation - New research direction for viral hemorrhagic fevers
por: Małkowska, Paulina, et al.
Publicado: (2022)

Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling
por: Song, Jia, et al.
Publicado: (2022)

Porcine IKKε is involved in the STING-induced type I IFN antiviral response of the cytosolic DNA signaling pathway
por: Luo, Jia, et al.
Publicado: (2023)

The Signal Peptide and Chaperone UNC93B1 Both Influence TLR8 Ectodomain Intracellular Endosomal Localization
por: Ao, Da, et al.
Publicado: (2021)

Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5
por: Weerawardhana, Asela, et al.
Publicado: (2022)

RIG-I in RNA virus recognition
por: Kell, Alison M., et al.
Publicado: (2015)

Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5
por: Louber, Jade, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jfaqaneat086lqung7sjv1ej3l