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Gene-environment interactions mediate stress susceptibility and resilience through the CaMKIIβ/TARPγ-8/AMPAR pathway
Although stressful events predispose individuals to psychiatric disorders, such as depression, not all people who undergo a stressful life experience become depressed, suggesting that gene-environment interactions (GxE) determine depression risk. The ventral hippocampus (vHPC) plays key roles in mot...
Autores principales: | Sakai, Yusuke, Li, Haiyan, Inaba, Hiromichi, Funayama, Yuki, Ishimori, Erina, Kawatake-Kuno, Ayako, Yamagata, Hirotaka, Seki, Tomoe, Hobara, Teruyuki, Nakagawa, Shin, Watanabe, Yoshifumi, Tomita, Susumu, Murai, Toshiya, Uchida, Shusaku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170005/ https://www.ncbi.nlm.nih.gov/pubmed/34113835 http://dx.doi.org/10.1016/j.isci.2021.102504 |
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