Cargando…

Emerging Role of m(6) A Methylome in Brain Development: Implications for Neurological Disorders and Potential Treatment

Dynamic modification of RNA affords proximal regulation of gene expression triggered by non-genomic or environmental changes. One such epitranscriptomic alteration in RNA metabolism is the installation of a methyl group on adenosine [N(6)-methyladenosine (m(6)A)] known to be the most prevalent modif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sokpor, Godwin, Xie, Yuanbin, Nguyen, Huu P., Tuoc, Tran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170044/ https://www.ncbi.nlm.nih.gov/pubmed/34095121 http://dx.doi.org/10.3389/fcell.2021.656849

Ejemplares similares

BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrain
por: Nguyen, Huong, et al.
Publicado: (2022)

Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain
por: Abbas, Eman, et al.
Publicado: (2021)

Regulation of Cell Delamination During Cortical Neurodevelopment and Implication for Brain Disorders
por: Sokpor, Godwin, et al.
Publicado: (2022)

Context-specific chromatin remodeling activity of mSWI/SNF complexes depends on the epigenetic landscape
por: Sokpor, Godwin, et al.
Publicado: (2021)

Chromatin Remodeling BAF (SWI/SNF) Complexes in Neural Development and Disorders
por: Sokpor, Godwin, et al.
Publicado: (2017)

Safeguarding transcriptional memory: a mitotic bookmarking role for chromatin remodelers
por: Sokpor, Godwin, et al.
Publicado: (2023)

Dynamics of m6A RNA Methylome on the Hallmarks of Hepatocellular Carcinoma
por: Sivasudhan, Enakshi, et al.
Publicado: (2021)

Transcriptome-Wide m6A Methylome and m6A-Modified Gene Analysis in Asthma
por: Sun, Deyang, et al.
Publicado: (2022)

Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Pterygium by MeRIP Sequencing
por: Jiang, Yaping, et al.
Publicado: (2021)

Mapping of domain-mediated protein-protein interaction by SPOT peptide assay
por: Mao, Xiaoyi, et al.
Publicado: (2021)

Integrated Study of Transcriptome-wide m(6)A Methylome Reveals Novel Insights Into the Character and Function of m(6)A Methylation During Yak Adipocyte Differentiation
por: Zhang, Yongfeng, et al.
Publicado: (2021)

Transcriptome-wide N (6)-Methyladenosine Methylome Profiling Reveals m(6)A Regulation of Skeletal Myoblast Differentiation in Cattle (Bos taurus)
por: Yang, Xinran, et al.
Publicado: (2021)

Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue
por: Sakib, M. Sadman, et al.
Publicado: (2021)

Comprehensive analysis of differences in N6-methyladenosine RNA methylomes in Helicobacter pylori infection
por: Li, Huan, et al.
Publicado: (2023)

Bone-Derived Modulators That Regulate Brain Function: Emerging Therapeutic Targets for Neurological Disorders
por: Chen, Hongzhen, et al.
Publicado: (2021)

The Emerging Role of m6A Modification in Regulating the Immune System and Autoimmune Diseases
por: Wang, Yimeng, et al.
Publicado: (2021)

m(6)A: An Emerging Role in Programmed Cell Death
por: Tang, Fajuan, et al.
Publicado: (2022)

Developmental Functions of the Dynamic DNA Methylome and Hydroxymethylome in the Mouse and Zebrafish: Similarities and Differences
por: Jessop, Peter, et al.
Publicado: (2018)

The Complex Roles and Therapeutic Implications of m(6)A Modifications in Breast Cancer
por: Wei, Min, et al.
Publicado: (2021)

Methylomic Changes of Autophagy-Related Genes by Legionella Effector Lpg2936 in Infected Macrophages
por: Abd El Maksoud, Ahmed I., et al.
Publicado: (2020)

Characterization of DNA Methylomic Signatures in Induced Pluripotent Stem Cells During Neuronal Differentiation
por: Imm, Jennifer, et al.
Publicado: (2021)

HGF and MET: From Brain Development to Neurological Disorders
por: Desole, Claudia, et al.
Publicado: (2021)

The Application of Brain Organoids: From Neuronal Development to Neurological Diseases
por: Shou, Yikai, et al.
Publicado: (2020)

The Implication of STEP in Synaptic Plasticity and Cognitive Impairments in Alzheimer’s Disease and Other Neurological Disorders
por: Mahaman, Yacoubou Abdoul Razak, et al.
Publicado: (2021)

Differential Transcriptomes and Methylomes of Trophoblast Stem Cells From Naturally-Fertilized and Somatic Cell Nuclear-Transferred Embryos
por: Sun, Jin, et al.
Publicado: (2021)

Integrative Genome-Wide DNA Methylome and Transcriptome Analysis of Ovaries from Hu Sheep with High and Low Prolific
por: Yao, Xiaolei, et al.
Publicado: (2022)

Integration of Transcriptome and Methylome Highlights the Roles of Cell Cycle and Hippo Signaling Pathway in Flatfish Sexual Size Dimorphism
por: Wang, Na, et al.
Publicado: (2021)

The Maternal Microbiome Programs the m(6)A Epitranscriptome of the Mouse Fetal Brain and Intestine
por: Xiao, Zhuoyu, et al.
Publicado: (2022)

The emerging role of m(6)A modification of non-coding RNA in gastrointestinal cancers: a comprehensive review
por: Wang, Meiqi, et al.
Publicado: (2023)

Transcriptional expression of m(6)A and m(5)C RNA methyltransferase genes in the brain and fat body of honey bee adult workers
por: Bataglia, Luana, et al.
Publicado: (2022)

m(6)A Reader: Epitranscriptome Target Prediction and Functional Characterization of N(6)-Methyladenosine (m(6)A) Readers
por: Zhen, Di, et al.
Publicado: (2020)

Dynamic m(6)A mRNA Methylation Reveals the Role of METTL3/14-m(6)A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration
por: Xie, Shu-Juan, et al.
Publicado: (2021)

Transcriptome and DNA methylome analysis of peripheral blood samples reveals incomplete restoration and transposable element activation after 3-months recovery of COVID-19
por: Yin, Ying, et al.
Publicado: (2022)

The m(6)A-methylated mRNA pattern and the activation of the Wnt signaling pathway under the hyper-m(6)A-modifying condition in the keloid
por: Lin, Can-Xiang, et al.
Publicado: (2022)

Functional Implications of Active N(6)-Methyladenosine in Plants
por: Zheng, Hongxiang, et al.
Publicado: (2020)

Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner
por: Sokpor, Godwin, et al.
Publicado: (2021)

m6A Regulators Is Differently Expressed and Correlated With Immune Response of Esophageal Cancer
por: Zhao, Huaying, et al.
Publicado: (2021)

Corrigendum: The m(6)A-methylated mRNA pattern and the activation of the Wnt signaling pathway under the hyper-m(6)A-modifying condition in the keloid
por: Lin, Can-Xiang, et al.
Publicado: (2023)

Regulatory Role of N6-Methyladenosine (m6A) Modification in Osteoarthritis
por: Zhai, Ganggang, et al.
Publicado: (2022)

Hearing Loss in Neurological Disorders
por: Li, Siyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s83h8ff8n92503gj248ruam0d2